Search on: MULTIPLE ENDOCRINE NEOPLASIA 
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Descriptor English:   Multiple Endocrine Neoplasia 
Descriptor Spanish:   Neoplasia Endocrina Múltiple 
Descriptor Portuguese:   Neoplasia Endócrina Múltipla 
Synonyms English:   Adenomatosis, Familial Endocrine
Endocrine Neoplasia, Multiple
Neoplasia, Multiple Endocrine
Neoplasms, Multiple Endocrine  
Tree Number:   C04.588.322.400
C04.651.600
C04.700.630
C16.320.700.630
C19.344.400
Definition English:   A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively. 
Indexing Annotation English:   general or unspecified; prefer specifics; coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent; DF MULTIPLE ENDOCRINE NEOPL
History Note English:   95; was NEOPLASMS, MULTIPLE ENDOCRINE 1983-94; was ADENOMATOSIS, FAMILIAL ENDOCRINE 1965-82 (Prov 1964) 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SC secondary
SE secretion SU surgery
TH therapy US ultrasonography
UL ultrastructure UR urine
VE veterinary VI virology
Record Number:   22577 
Unique Identifier:   D009377 

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